Gonzatti MB, Goldberg EL. (2024) Ketone bodies as chemical signals for the immune system. Am J Physiol Cell Physioldoi: 10.1152/ajpcell.00478.2023
Tsusaka T, Najar MA, Schwarz B, Bohrnsen E, Oses-Prieto JA, Lee C, Burlingame AL, Bosio CM, Burslem GM, Goldberg EL. (2023) Reversible histone deacetylase activity catalyzes lysine acylation. bioRxivdoi: 10.1101/2023.11.17.567549
Tsusaka T, Oses-Prieto JA, Lee C, DeFelice BC, Burlingame AL, Goldberg EL. (2023) Non-specific recognition of histone modifications by H3K9bhb antibody. iSciencedoi: 10.1016/j.isci.2023.107235
Goldberg EL, Letian A, Dlugos T, Leveau C, Dixit VD. (2023) Innate Immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation. J Biol Chemdoi: 10.1016/j.jbc.2023.103005
Zhang X, McDonald JG, Aryal B, Canfrán-Duque A, Goldberg EL, Araldi E, Ding W, Fan Y, Thompson BM, Singh AK, Li Q, Tellides G, Ordovás-Montanes J, García Milian R, Dixit VD, Ikonen E, Suárez Y, Fernández-Hernando C. (2021) Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis. PNAS DOI: 10.1073/pnas.2107682118
Goldberg, E.L., Dixit, V.D. Bone Marrow: An Immunometabolic Refuge during Energy Depletion. Cell Metab. 2019 Oct 1;30(4):621-623. PMID: 31577929
Camporez J.P., Lyu K., Goldberg E.L., Zhang D., Cline G.W., Jurczak M.J., Dixit V.D., Petersen K.F., Shulman G.I. Anti-inflammatory effects of estrogen mediate the sexual dimorphic response to lipid-induced insulin resistance. J Physiol. 2019 June 17. PMID: 31206703
Camell CD, Sander J, Spadaro O, Lee A, Nguyen KY, Wing A, Goldberg EL, Youm YH, Brown CW, Elsworth J, Rodeheffer MS, Schultze JL, Dixit VD. Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. Nature. 2017 Oct 5;550(7674):119-123. PMID: 28953873
Goldberg, E.L. and Dixit,V.D. (2017) Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation. Molecular Metabolism Jan 3;6(2):219-225. PMID 28180063
Spadaro O., Goldberg, E.L., Camell, C.D., Youm, Y., Kopchick, J.J., Nguyen, K.Y., Bartke, A., Sun, L.Y., Dixit, V.D. (2016) Growth hormone receptor deficiency protects against age-related NLRP3 inflammasome activation and immune-senescence. Cell Reports Feb 23;14(7):1571-80. PMID 26876170
Youm, Y.H., Nguyen, K.Y., Grant, R.W., Goldberg, E.L., Bodogai, M., Kim, D., D’Agostine, D., Planavsky, N., Lupfer, C., Kanneganti, T.D., Kang, S., Horvath, T.L., Fahmy, T.M., Crawford, P.A., Biragyn, A., Alnemri, E., Dixit, V.D. (2015) The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat. Med. 21(3):263-9. PMID: 25686106.
Goldberg, E.L. and Dixit, V.D. (2015) “Crowning” eosinophils in adipose tissue: does location matter? J Leukoc Biol. Oct;98(4):451-2. PMID 26429777
Camell, C., Goldberg, E., Dixit, V.D. (2015) Regulation of Nlrp3 inflammasome by dietary metabolites. Seminars in Immunology 27:334-342. PMID 26776831
Goldberg, E.L. and Dixit, V.D. (2015) Drivers of age-related inflammation and strategies for healthspan extension. Immunol Rev. 265(1):63-74. PMID 25879284
Goldberg, E.L., Romero-Aleshire, M.J., Renkema, K.R., Ventevogel, M.S., Chew, W.M., Uhrlaub, J.L., Smithey, M.J., Limesand, K.H., Sempowski, G.D., Brooks, H.L., Nikolich-Zugich, J. (2015) Lifespan-extending calorie restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms. Aging Cell. 14(1): 130-8. PMID: 25424641.
Goldberg, E.L., Smithey, M.J., Lutes, L.K., Uhrlaub, J.L., Nikolich-Zugich, J. (2014) Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections. J Immunol. 193(2): 757-63. PMID: 24913978.
Kusne, Y.*, Goldberg, E.L.*, Parker, S.S., Hapak, S.M., Maskaykina, I.Y., Chew, W.M., Limesand, K.H., Brooks, H.L., Price, T.J., Sanai, N., Nikolich-Zugich, J., Ghosh, S. (2014) Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice. Age (Dordr). 36(1): 199-212. PMID: 23949159. *Authors contributed equally
Rudd, B.D., Venturi, V., Smith, N.L., Nzingha, K., Goldberg, E.L., Li, G., Nikolich-Zugich, J., Davenport, M.P. (2013) Acute neonatal infections ‘lock-in’ a suboptimal CD8+ T cell repertoire with impaired recall responses. PLoS Pathog. 9(9):e1003572. PMID: 24068921.